RATS HIGHLY SUSCEPTIBLE TO EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS OBTAINED BY CROSSING RATS FROM STRAINS WITH LOW SUSCEPTIBILITY
✍ Scribed by Källén, Bengt
- Book ID
- 114830620
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 474 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0960-7420
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## Abstract A substrain of the Lewis rat, Lew/Mol, differing from ordinary Lewis rats in that it is hardly susceptible to the induction of experimental autoimmune encephalomyelitis (EAE) is described. The Lew/Mol rats did not mount a host‐vs. ‐graft response towards cells from an EAE‐susceptible su
Experimental autoimmune neuritis (EAN) is a CD4 1 Tcell-mediated inflammatory demyelinating disease of the peripheral nervous system (PNS) that serves as a model for Guillain-Barre ´syndrome (GBS) in humans. Various rat strains show different susceptibility to EAN. We examined PNS myelin-induced T-a