Humoral Response Against Myelin Antigens in Two Strains of Rats with Different Susceptibility to Experimental Allergic Encephalomyelitis (EAE)
β Scribed by Rivero, Virginia E.; Riera, Clelia M.; Roth, German A.
- Book ID
- 118269964
- Publisher
- Informa plc
- Year
- 1999
- Tongue
- English
- Weight
- 756 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0891-6934
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Experimental autoimmune neuritis (EAN) is a CD4 Ψ T cell-mediated, inflammatory demyelinating disease of the peripheral nervous system (PNS) that serves as a model for Guillain-Barre Β΄syndrome (GBS) in humans. Various mouse and rat strains show different susceptibilities to EAN that can be induced b
Albino Oxford (AO) rats, unlike Dark Agouti (DA) rats are resistant to the induction of experimental autoimmune encephalomyelitis (EAE). The reason for the resistance could be some restraining mechanism preventing auto-aggressive cell activation at the level of draining lymph nodes (DLN) during the