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Rational screenning in combinatorial peptide libraries of protein functional loop

✍ Scribed by Weizhong Li; Zhijie Liu; Shide Liang; Yuzhen Han; Luhua Lai

Book ID
105726914
Publisher
Springer
Year
1999
Tongue
English
Weight
590 KB
Volume
44
Category
Article
ISSN
1001-6538

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Rational design and combinatorial chemistry were utilized to search for lead protein L (PpL) mimetics for application as affinity ligands for the purification of antibodies and small fragments, such as Fab and scFv, and as potential diagnostic or therapeutic agents. Inspection of the key structural