𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Rational design of the survivin/CDK4 complex by combining protein–protein docking and molecular dynamics simulations

✍ Scribed by Selent, Jana; Kaczor, Agnieszka A.; Guixà-González, Ramon; Carrió, Pau; Pastor, Manuel; Obiol-Pardo, Cristian

Book ID
119993028
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
581 KB
Volume
19
Category
Article
ISSN
1610-2940

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Protein-Protein Complexes (Analysis, Mod
Protein-Protein Complexes (Analysis, Modeling and Drug Design) || Protein Dynamics and Drug Design: The Role of Molecular Simulations
✍ Zacharias, Martin 📂 Article 📅 2010 🏛 IMPERIAL COLLEGE PRESS 🌐 English ⚖ 1005 KB

Given the immense progress achieved in elucidating protein-protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can

Molecular dynamics simulation and automa
Molecular dynamics simulation and automated docking of the pro-apoptotic bax protein and its complex with a peptide designed from the Bax-binding domain of anti-apoptotic Ku70
✍ Fabrizio Mancinelli; Michele Caraglia; Alfredo Budillon; Alberto Abbruzzese; Ett 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 399 KB

## Abstract Bax, a multi‐domain protein belonging to the large family of Bcl‐2 proteins, has a pivotal role for the initiation of the cytochrome __c__‐mediated apoptosis, a vital physiologic process to eliminate damaged or unwanted cells. In response to specific stimuli Bax translocates from cytoso