Rational design of chiral stationary phases for capillary supercritical fluid chromatography.
β Scribed by Bryant E. Rossiter; Patrik Petersson; Deborah F. Johnson; Masakatsu Eguchi; Jerald S. Bradshaw; Karin E. Markides; Milton L. Lee
- Book ID
- 104216187
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 249 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
A new class of chiral copolymers consisting of chiral organic and dimethylsiloxane units is described. One example of such copolymers, containing alternating diamide and dimethylsiloxane units, has been synthesized.
Using these chiral materials as stationary phases in capillary columns, chiral diols can be efficiently resolved by supercritical fluid chromatography.
π SIMILAR VOLUMES
Vancomycin immobilized on an aldehyde functionalized silica support in packed capillary columns has been used as a chiral stationary phase in supercritical fluid chromatography under subcritical conditions. The use of carbon dioxide with methanol as the mobile phase modifier is shown to offer an ext