Hepatocyte DNA syntheGs, initiated by epidermal growth factor (EGF), is reversibly inhibited by 2% dimethyl sulfoxide (DMSO). At that concentration, both the survival of the cells in culture and the expression of differentiated functions are prolonged. DMSO does not affect thymidine uptake or EGF re
Rat small hepatocytes for liver support: growth and metabolic activities in culture
β Scribed by H. Kamachi; M. Matsushita; H. Okubo; T. Kawai; K. Nishikawa; T. Fujimoto; S. Todo
- Book ID
- 106256966
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 171 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1434-7229
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Liver regeneration factor belongs to the leucinezipper family of transcription factors. It was originally cloned and characterized through differential screening of a regenerating rat liver cDNA library. The mRNA for liver regeneration factor-1 is barely detectable in normal rat liver but is dramati
In the present study, we showed the role of the liver-enriched transcription factors in the transition during which proliferating hepatocytes become quiescent. We used primary rat hepatocytes cultured in modified L-15 medium. The cells proliferated and, after the addition of 2% dimethyl sulfoxide (D
Many hepatocellular activities may be proximally regulated by intracellular signalling proteins including mitogen-activated protein kinases (MAPK). In this study, signalling events from epidermal growth factor (EGF) and insulin were examined in primary cultured human and rat hepatocytes. Using Weste