Rat liver flavin-containing monooxygenase (FMO): cDNA cloning and expression in yeast
โ Scribed by Kunio Itoh; Teruyuki Kimura; Tsuyoshi Yokoi; Susumu Itoh; Tetsuya Kamataki
- Book ID
- 113262892
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 587 KB
- Volume
- 1173
- Category
- Article
- ISSN
- 0167-4781
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Full-length cDNA clones encoding FMO1 and FMO5 have been isolated from a library constructed with mRNA from the liver of a female CD-1 mouse. The derived sequence of FMO1 contains 2310 bases: 1596 in the coding region, 301 in the 5'-flanking region, and 413 in the 3'-flanking region. The sequence fo
Hepatic flavin-containing monooxygenase (FMO) activity of microsomes from adult CD-1, Swiss-Webster, C57BL/6, and DBA/2 mice was found to be significantly higher in females than in males. Based on protein and mRNA levels in CD-1 mice, FMO forms responsible for the gender difference in FMO activity w