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Rat cardiac hypertrophy Altered sodium-calcium exchange activity in sarcolemmal vesicles

✍ Scribed by Remy Hanf; Isabelle Drubaix; Françoise Marotte; Lionel G. Lelievre

Book ID
115920446
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
462 KB
Volume
236
Category
Article
ISSN
0014-5793

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Effect of platelet-activating factor (PAF) on sodium calcium exchange in cardiac sarcolemmal vesicles
✍ He-Ping Meng; Michael J. B. Kutryk; Grant N. Pierce 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 527 KB

The effects of platelet-activating factor (PAF) on Na(+)-dependent calcium uptake in myocardial sarcolemmal vesicles were examined in order to clarify its mechanism of inotropic action on the heart. PAF (40 and 20 microM) significantly inhibited Na(+)-Ca2+ exchange by 61% and 37%, respectively. Both