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RasGRP3 mediates phorbol ester-induced, protein kinase C-independent exocytosis

โœ Scribed by Nobuaki Ozaki; Yoshitaka Miura; Tsutomu Yamada; Yoshiro Kato; Yutaka Oiso


Book ID
116290055
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
637 KB
Volume
329
Category
Article
ISSN
0006-291X

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The signal transduction mechanism of protein kinase FA/GSK-3a by tyrosine phosphorylation in A431 cells was investigated using calphostin C as an inhibitor for protein kinase C (PKC). Kinase F A / C S K -~~ could be tyrosine-dephosphorylated and inactivated to -10% of control in a concentration-depe