Ras protein p21 processing enzyme farnes
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Rajesh Agarwal; Sikandar G. Khan; Mohammad Athar; Syed I. A. Zaidi; David R. Bic
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Article
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1993
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John Wiley and Sons
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English
β 869 KB
## Abstract Farnesylation of ras protein p21 is crucial for the protein's membrane localization, which is essential for its cellβtransforming activity, which in turn is thought to be critical for the ultimate induction of cancer. The cytosolic enzyme farnesyltransferase plays a major role in posttr