## Abstract Farnesylation of ras protein p21 is crucial for the protein's membrane localization, which is essential for its cellโtransforming activity, which in turn is thought to be critical for the ultimate induction of cancer. The cytosolic enzyme farnesyltransferase plays a major role in posttr
Ras p21 farnesylation in ultraviolet radiation-induced tumors in murine skin
โ Scribed by Agarwal, R.; Khan, S.G.; Mukhtar, H.
- Book ID
- 122751474
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 155 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0923-1811
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The activation of ras proto-oncogenes by point mutation in a broad spectrum of clinical malignancies and experimentally induced tumors suggests their critical role in cancer induction. To determine whether the activation of ras proto-oncogenes by point mutation also contributes to ultraviolet B radi