Ras protein is involved in the physiological regulation of phospholipase D by platelet derived growth factor
✍ Scribed by Lucas, Luisa; del Peso, Luis; Rodríguez, Pilar; Penalva, Verónica; Lacal, Juan Carlos
- Book ID
- 110062676
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 328 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0950-9232
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Abbreviations: HSC, hepatic stellate cells; ␣-SMA, ␣ smooth muscle actin; PDGF, platelet-derived growth factor; PPAR␥, peroxisome proliferator-activated receptor ␥; 9-cisRA, 9-cis retinoic acid; RXR, retinoic X receptor; 15d-PGJ 2 , 15-deoxy-⌬ 12,14 prostaglandin J 2 ; [ 3 H]TdR, [methyl-3 H]thymidi
## Abstract Phospholipase D (PLD) is implicated in a variety of physiological processes that reveal it to be a member of the signal transducing phospholipases. We found that PLD1 is activated when basic fibroblast growth factor (bFGF) stimulates neurite outgrowth of an immortalized hippocampal cell