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Ras oncogene and p53 gene hotspot mutations in colorectal cancers

✍ Scribed by SHYR-YI LIN; PAO-HUEI CHEN; MING-JUI YANG; TE-CHUAN CHEN; CHIH-PENG CHANG; JAN-GOWTH CHANG

Book ID
115170718
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
950 KB
Volume
10
Category
Article
ISSN
0815-9319

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## Abstract Gene mutations in __APC__, __K‐ras__, and __p53__ are thought to be essential events for colorectal cancer development. Recent data seem to indicate that __K‐ras__ and __p53__ mutations rarely co‐exist in the same tumor, indicating that these alterations do not represent a synergistic e