Rapid determination of losartan and losa
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Hiten J. Shah; Mohan L. Kundlik; Nitesh K. Patel; Gunta Subbaiah; Dasharath M. P
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Article
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2009
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John Wiley and Sons
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English
⚖ 643 KB
## Abstract A rapid LC–MS/MS method has been developed and validated for the determination of losartan (LOS) and its metabolite losartan acid (LA) (EXP‐3174) in human plasma using multiplexing technique (two HPLC units connected to one MS/MS). LOS and LA were extracted from human plasma by SPE tech