A sensitive and specific LC/MS/MS method for the determination of L-hyoscyamine was developed and validated over the linearity range 20-500 pg ml-1 with 1.0 ml of plasma using scopolamine as the internal standard. The API III-Plus LC/MS/MS was operated under the multiple reaction monitoring mode usi
Rapid and Selective LC–MS–MS Method for the Determination ofcyclo-trans-4-l-Hydroxyprolyl-l-serine (JBP485) in Rat Plasma
✍ Scribed by Changyuan Wang; Jian Cang; Qi Liu; Qiang Meng; Huijun Sun; Ying Gao; Decheng Lv; Taiichi Kaku; Kexin Liu
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 381 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0009-5893
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A sensitive LC-MS-MS method capable of quantifying terfenadine at levels down to 100 pg ml-1 in human plasma is reported. The method was validated over a linear range from 0.1 to 5.0 ng ml-1 using a liquid-liquid extraction with a deuterium-labelled internal standard. The between-run precision and a
## Abstract A highly sensitive, rapid assay method has been developed and validated for the simultaneous estimation of tolmetin (TMT) and MED5 in human plasma with liquid chromatography coupled to tandem mass spectrometry with electrospray ionization in the positive‐ion mode. A simple solid‐phase e