## Purpose: To evaluate the feasibility and reproducibility of a noninvasive, rapid and quantitative pulmonary perfusion mapping method using a two-compartment tissue model in combination with a (1)h spin labeling technique. ## Materials and methods: Ten healthy volunteers and three patients with
Rapid quantitative lung 1H T1 mapping
β Scribed by Peter M. Jakob; Claudia M. Hillenbrand; Tungte Wang; Georg Schultz; Dietbert Hahn; Axel Haase
- Book ID
- 102376247
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 281 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1053-1807
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β¦ Synopsis
Abstract
In this contribution, a rapid and robust technique for quantitative T~1~ mapping of the human lung is presented. Based on a series of Snapshot FLASH tomograms acquired after a single inversion pulse, high quality and quantitative T~1~ parameter maps acquired in under five seconds were obtained from six healthy volunteers. The measured T~1~ values are in good agreement with previously reported literature values. T~1~ maps were also acquired with the volunteers breathing room air or 100% O~2~. The T~1~ difference between breathing room air and 100% O~2~ is statistically significant at P < 0.0001. J. Magn. Reson. Imaging 2001;14:795β799. Β© 2001 WileyβLiss, Inc.
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