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Rapid publication: Constitutive expression of a vitamin D 1-hydroxylase in a myelomonocytic cell line: A model for studying 1,25-dihydroxyvitamin D production in vitro

✍ Scribed by Dr. John S. Adams; Timothy G. Beeker; Takashi Hongo; Thomas L. Clemens

Book ID: 112118634
Publisher: American Society for Bone and Mineral Research
Year: 2009
Tongue: English
Weight: 420 KB
Volume: 5
Category: Article
ISSN: 0884-0431
DOI: 10.1002/jbmr.5650051212

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Treatment of avian myelomonocytic cells with 1,25-dihydroxyvitamin D 3 (1,25(OH)2D3) results in an approximately two fold increase in levels of Na,K-ATPase b1 subunit mRNA and protein (both total and plasma membrane-associated). The changes in b1 subunit expression occur in the absence of a detectab