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Rapid progression of prostate cancer in men with a BRCA2 mutation

✍ Scribed by Narod, S A; Neuhausen, S; Vichodez, G; Armel, S; Lynch, H T; Ghadirian, P; Cummings, S; Olopade, O; Stoppa-Lyonnet, D; Couch, F

Book ID
109999547
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
107 KB
Volume
99
Category
Article
ISSN
0007-0920

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BACKGROUND. Families with a high incidence of hereditary breast cancer, and subsequently shown to have terminating mutations in BRCA1 or BRCA2, appear to have a higher incidence of prostate cancer among male relatives. We aimed to determine whether the common germline mutations of BRCA1 or BRCA2 in