Rapid peptide synthesis: Synthesis of human fibrinopeptide A

✍ Scribed by Brian J. Johnson; William P. May

• Publisher: John Wiley and Sons
• Year: 1969
• Tongue: English
• Weight: 127 KB
• Volume: 58
• Category: Article
• ISSN: 0022-3549
• DOI: 10.1002/jps.2600581240

✦ Synopsis

pental was bound when a sixteen-fold molar excess of TCA (a similar excess to that used in the in vivo experiments) was incorporated into the buffer. This suggests a competitive protein binding phenomenon that may account for the above differences, and pharmacologically inert but highly protein bound materials such as TCA may have a role in pharmaceutical formulations, particularly those parenterally administered.