## Abstract Microwaveβassisted (MW) reactions are of special interest to the chemical community due to faster reaction times, cleaner reactions and higher product yields. The adaptation of MW to solid phase peptide synthesis resulted in spectacular syntheses of difficult peptides. In the case of Me
Rapid Microwave-Assisted CNBr Cleavage of Bead-Bound Peptides
β Scribed by Lee, Su Seong; Lim, Jaehong; Cha, Junhoe; Tan, Sylvia; Heath, James R.
- Book ID
- 115459460
- Publisher
- American Chemical Society
- Year
- 2008
- Tongue
- English
- Weight
- 780 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1520-4766
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π SIMILAR VOLUMES
Consecutive enzymatic reactions on analytes affinity-bound to immobilized metal ion beads with subsequent direct analysis of the products by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry have been used for detecting protein synthesis errors occuring at the N-terminus.
## Abstract A new microwaveβenhanced method for rapid demethylation of methyl phenyl ethers using neat methanesulfonic acid (CH~3~SO~3~H) is presented. Using a monomodal microwave cavity, cleavage of anisole (**1**), used as model compound, to phenol (**2**) was achieved with high conversions (ca 8