Rapid in vitro chemosensitivity analysis of human colon tumor cell lines
โ Scribed by Dirk S Waldenmaier; Alexandra Babarina; Frank C Kischkel
- Book ID
- 114087153
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 396 KB
- Volume
- 192
- Category
- Article
- ISSN
- 0041-008X
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The use of well-characterized human lung cancer cell lines has allowed for new opportunities in preclinical and clinical drug evaluation. Development of semiautomated tests of in vitro cytotoxicity such as the MTT assay, which utilizes the formazan salt 3-(4,~-dimethylthiazol-2-yl)-2,S-diphenyltetra
Numerous procedures have been described which test the chemosensitivity of tumor cell lines. A major disadvantage of most of these assays is that practical limitations prevent the testing of more than a few variables. We have adapted a rapid and efficient colorimetric assay for testing the chemosens