Maternal allo-immunization to antigens of the Duffy blood group system can result in haemolytic disease of the newborn (HDN), therefore, the application of allele-specific polymerase chain reaction (ASPCR) for prenatal genotyping of the Duffy antigen system to identify pregnancies at risk for HDN wa
Rapid genotyping of blood group antigens by multiplex polymerase chain reaction and DNA microarray hybridization
β Scribed by Sigrid H.W. Beiboer; Tinka Wieringa-Jelsma; Petra A. Maaskant-Van Wijk; C. Ellen Van Der Schoot; Rob Van Zwieten; Dirk Roos; Johan T. Den Dunnen; Masja De Haas
- Book ID
- 109143024
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 301 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0372-1248
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An allele-specific polymerase chain reaction (ASPCR) assay for prenatal genotyping of the Kidd antigen system in order to identify pregnancies at risk for haemolytic disease of the newborn (HDN) was developed. Oligonucleotide primers were designed for ASPCR of JKA and JKB. A validation study was per
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