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Rapid, direct determination of trace amounts of salicyclic acid in deproteinized serum by means of high-pressure liquid—liquid chromatography

✍ Scribed by C.P. Terweij-Groen; T. Vahlkamp; J.C. Kraak


Book ID
108448144
Publisher
Elsevier Science
Year
1978
Weight
601 KB
Volume
145
Category
Article
ISSN
0378-4347

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A quantitative high-pressure liquid chromatographic method has been developed for the analysis of hydrochlorothiazide in serum in therapeutical concentrations. The method is based on gel filtration of the sera on Sephadex G-15, extraction of the protein-free fraction of the efHuent with ethyl acetat