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Rapid diagnosis of tuberculous meningitis by polymerase chain reaction assay of cerebrospinal fluid

โœ Scribed by Juei-Jueng Lin; Horng-Jyh Harn; Yaw-Don Hsu; Wen-Long Tsao; Herng-Sheng Lee; Wei-Hwa Lee


Publisher
Springer
Year
1995
Tongue
English
Weight
599 KB
Volume
242
Category
Article
ISSN
0340-5354

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Enzymed-linked immunosorbent assay (ELISA) was used to detect mycobacterial antigen and antimycobacterial antibody in cerebrospinal fluid (CSF) specimens of 50 patients with tuberculous meningitis (TBM) and 50 patients with non-tuberculous neurological diseases (control group). The assay gave no fal

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## Abstract Herpes simplex virus thymidine kinase gene specific polymerase chain reaction (PCR) amplification of DNA extracted from lumber cerebrospinal fluid (CSF) and Southern blotting (SB) were evaluated as a method for the diagnosis of herpes simplex encephalitis (HSE). Positive PCRโ€SB results