Selected aneuploidies can be rapidly diagnosed by the analysis of fluorescent polymerase chain reaction (PCR) products of chromosomespecific and highly polymorphic small tandem repeats (STRs). The quantitative STR patterns obtained from samples of normal individuals are markedly different from those
Rapid detection of aneuploidies by microsatellite and the quantitative fluorescent polymerase chain reaction
β Scribed by Matteo Adinolfi; Barbara Pertl; Jon Sherlock
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 222 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0197-3851
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β¦ Synopsis
Several studies have been performed to assess the diagnostic value of using small tandem repeat (STR) markers and quantitative fluorescent polymerase chain reaction (QF-PCR) assays for the rapid detection of aneuploidies involving chromosomes
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