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Rapid, Continuous Solution-Phase Peptide Synthesis: Application to Peptides of Pharmaceutical Interest†

✍ Scribed by Carpino, Louis A.; Ghassemi, Shahnaz; Ionescu, Dumitru; Ismail, Mohamed; Sadat-Aalaee, Dean; Truran, George A.; Mansour, E. M. E.; Siwruk, Gary A.; Eynon, John S.; Morgan, Barry

Book ID
111929564
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
138 KB
Volume
7
Category
Article
ISSN
1083-6160

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A practical modification of the Weinreb amidation protocol employing amino acids as the amine reaction partner has been developed that allows for the facile synthesis of oligopeptides in solution.