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Rapid and sensitive high-performance liquid chromatographic assay for novobiocin in human serum

โœ Scribed by Eleanor G. Zuhowski; John C. Gutheil; Merrill J. Egorin

Publisher
Elsevier Science
Year
1994
Weight
325 KB
Volume
655
Category
Article
ISSN
0378-4347

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A rapid and specific HPLC assay for quantitative determination of bupivacaine in human serum is described. The technique incorporates an on-line sample clean-up system followed by reversed-phase chromatography with UV detection. The proposed method uses a column-switching technique and protein-coat