Transforming growth factor-a and hepatocyte growth factor are important stimulators of hepatocyte proliferation. In this series of experiments we sought to measure the expression of transforming growth factor-a mRNA by hepatocytes in response to toxic liver injury produced by carbon tetrachloride or
โฆ LIBER โฆ
Rapid and marked induction of hepatocyte growth factor during liver regeneration after ischemic or crush injury
โ Scribed by Masahiro Hamanoue; Kouichi Kawaida; Sonshin Takao; Hisaaki Shimazu; Sumihare Noji; Kunio Matsumoto; Toshikazu Nakamura
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 916 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0270-9139
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Liver regeneration factor belongs to the leucinezipper family of transcription factors. It was originally cloned and characterized through differential screening of a regenerating rat liver cDNA library. The mRNA for liver regeneration factor-1 is barely detectable in normal rat liver but is dramati