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Rapid analysis of the DNA-binding specificities of transcription factors with DNA microarrays

โœ Scribed by Mukherjee, Sonali; Berger, Michael F; Jona, Ghil; Wang, Xun S; Muzzey, Dale; Snyder, Michael; Young, Richard A; Bulyk, Martha L


Book ID
109919080
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
556 KB
Volume
36
Category
Article
ISSN
1061-4036

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Nucleosome positioning is proposed to have an essential role in facilitating the regulated transcription of eukaryotic genes. Some transcription factors can bind to DNA when it is appropriately wrapped around the histone core, others cannot hind due to the severe deformation of DNA structure. The st