## Abstract Chemically modified silicon nanoparticles were applied for the laser desorption/negative ionization of small acids. A series of substituted sulfonic acids and fatty acids was studied. Compared to desorption ionization on porous silicon (DIOS) and other matrixβless laser desorption/ioniz
β¦ LIBER β¦
Rapid analysis of abused drugs using nanostructured silicon surface assisted laser desorption/ionization mass spectrometry
β Scribed by Cheng, Yu-Che; Chen, Kun-Han; Wang, Juo-Shin; Hsu, Wen-Liu; Chien, Chih-Cheng; Chen, Wen-Yih; Tsao, Chia-Wen
- Book ID
- 111874127
- Publisher
- Royal Society of Chemistry
- Year
- 2012
- Tongue
- English
- Weight
- 754 KB
- Volume
- 137
- Category
- Article
- ISSN
- 0003-2654
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## Abstract Matrixβassisted laser desorption/ionization mass spectrometry (MALDIβMS) has been used to directly analyze and image pharmaceutical compounds in intact tissue. The antiβtumor drug SCH 226374 was unambiguously determined in mouse tumor tissue using MALDIβQqTOFMS (QSTAR) by monitoring the