𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Rapid aggregation of tau protein into Alzheimer-like paired helical filaments reveals a nucleation-elongation mechanism

✍ Scribed by Martin von Bergen; Peter Friedhoff; Jacek Biernat; Eva-Maria Mandelkow; Eckhard Mandelkow


Book ID
117411383
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
192 KB
Volume
21
Category
Article
ISSN
0197-4580

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Rapid Assembly of Alzheimer-like Paired
✍ Friedhoff, Peter; Schneider, Anja; Mandelkow, Eva-Maria; Mandelkow, Eckhard πŸ“‚ Article πŸ“… 1998 πŸ› American Chemical Society 🌐 English βš– 189 KB

Alzheimer's disease is characterized by the progressive deposition of two types of fibers in the affected brains, the amyloid fibers (consisting of the Abeta peptide, generating the amyloid plaques) and paired helical filaments (PHFs, made up of tau protein, forming the neurofibrillary tangles). Whi