Rapid Access to Complex Molecular Architectures via o-Azaquinones

✍ Scribed by K. C. Nicolaou; Yong-Li Zhong; Phil S. Baran; Kazyuki Sugita

• Book ID: 101366173
• Publisher: John Wiley and Sons
• Year: 2001
• Tongue: English
• Weight: 162 KB
• Volume: 40
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/1521-3773(20010601)40:11<2145::aid-anie2145>3.0.co;2-m

✦ Synopsis

A multitude of natural product like molecules such as 2 and 3 can be readily obtained from hydroxyketoamide 1. The versatile 1 is derived, via the intermediate o-azaquinone 4, from the Dess-Martin periodinane oxidation of the corresponding anilide.