Rapid Access to Complex Molecular Archit
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K. C. Nicolaou; Yong-Li Zhong; Phil S. Baran; Kazyuki Sugita
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Article
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2001
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John Wiley and Sons
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English
β 162 KB
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A multitude of natural product like molecules such as 2 and 3 can be readily obtained from hydroxyketoamide 1. The versatile 1 is derived, via the intermediate o-azaquinone 4, from the Dess-Martin periodinane oxidation of the corresponding anilide.