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Rapamycin regulates synthesis of transforming growth factor-beta1 and extracellular matrix in arterial neointimal smooth muscle cells

✍ Scribed by Jeffery L. Walding; Jing Kang; Daniel Day; Martin Dalton; Walter Newman; Zhongbiao Wang


Book ID
113678158
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
44 KB
Volume
205
Category
Article
ISSN
1072-7515

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✍ Gouri Shanker; Dan Olson; Roger Bone; Rajinder Sawhney πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 372 KB

Transforming growth factor beta-1 (TGF-1 ), which is present in lung tissue, has been suggested to play a role in modulating vascular cell function in vivo. The action of TGF-1 in vivo, especially at the local site of application to connective tissue, is anabolic and leads to pulmonary fibrosis and