Cytoskeleton not only controls cell morphology but also regulates cell growth, migration, differentiation, and gene expression, events which are fundamental to embryogenesis, carcinogenesis, and wound healing. We have recently reported that reorganization of cytoskeleton induces expression of mRNA f
✦ LIBER ✦
Requirement of transforming growth factor β–activated kinase 1 for transforming growth factor β–induced α-smooth muscle actin expression and extracellular matrix contraction in fibroblasts
✍ Scribed by Xu Shi-Wen; Sunil K. Parapuram; Daphne Pala; Yunliang Chen; David E. Carter; Mark Eastwood; Christopher P. Denton; David J. Abraham; Andrew Leask
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 242 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0004-3591
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The profound effects of transforming growth factor b1 (TGF-b1) on the immune system, cardiogenesis, in yolk sac hematopoeisis and in differentiation of endothelium have been demonstrated by detailed analyses of TGF-b1 knockout mice during embryogenesis. We have systematically examined the autocrine