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Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism

✍ Scribed by Wan, X; Harkavy, B; Shen, N; Grohar, P; Helman, L J


Book ID
110071996
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
245 KB
Volume
26
Category
Article
ISSN
0950-9232

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## Abstract Previous work from our laboratory has shown that human ether Γ  go‐go (hEAG) K^+^ channels are crucial for breast cancer cell proliferation and cell cycle progression. In this study, we investigated the regulation of hEAG channels by an insulin‐like growth factor‐1 (IGF‐1), which is know