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IGF1R Signaling Is Necessary for FSH-Induced Activation of AKT and Differentiation of Human Cumulus Granulosa Cells

✍ Scribed by Baumgarten, Sarah C.; Convissar, Scott M.; Fierro, Michelle A.; Winston, Nicola J.; Scoccia, Bert; Stocco, Carlos


Book ID
124149884
Publisher
Endocrine Society
Year
2014
Tongue
English
Weight
393 KB
Volume
99
Category
Article
ISSN
0021-972X

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## Abstract Human mesenchymal stem cell (hMSC) differentiation into osteoblasts and the signaling events involved are poorly understood. We recently established that contact with specific extracellular matrix (ECM) proteins, in particular laminin‐5, is sufficient to induce an osteogenic phenotype i