Randomized, controlled pilot trial of interferonα (IFN) with or without thymosinα1 (TA1) in naive chronic hepatitis C (CHC)
✍ Scribed by A. Gramenzi; L. Di Giammarino; C. Cursaro; F. Felline; S. Talarico; A. D'Errico; R. Carella; M. Biselli; P. Andreone; M. Bernardi
- Book ID
- 119526351
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 112 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0168-8278
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Thymosin ␣ 1 (T␣) is an immune modifier that has been shown in a pilot study to be effective for chronic hepatitis B; this requires confirmation. Ninety-eight patients with clinicopathologically proven chronic hepatitis B were randomly allocated to 3 groups: 1) group A received a 26-week course of T
Hepatitis C is a major cause of liver disease leading to cirrhosis. Although interferon (IFN) is the only approved therapy, treatment is characterized by low response rates and dose-limiting side effects. We evaluated the addition of thymosin ␣1 (TA1), an immunomodulatory peptide, to the standard tr