Radiotherapy and combination chemotherapy in advanced Ewing's sarcoma–Intergroup study
✍ Scribed by Miljenko V. Pilepich; Teresa J. Vietti; Mark E. Nesbit; Melvin Tefft; John Kissane; E. Omer Burgert; Douglas Pritchard
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 535 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0008-543X
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## Abstract ## Background and Objectives Local therapy of pelvic Ewing's sarcoma remains a challenge because of the complex anatomy and large tumor volumes. Wide resections often end up contaminated with marginal margins in one part of the specimen. Pelvic tumor surgery causes considerable disabil
Based on studies of the chemotherapy of h u m a n leukemia and late stage animal neoplasms which may be kinetically analogous to disseminated reticulum cell sarcoma, a therapy program was devised using sequential cyclophosphamidevincristine followed by weekly methotrexate-cytosine arabinoside. Each