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Radiosynthesis of carbon-11 labelled N-methyl-2-(arylthio)benzylamines: potential radiotracers for the serotonin reuptake receptor

✍ Scribed by Alan A. Wilson; Sylvain Houle


Publisher
John Wiley and Sons
Year
1999
Tongue
French
Weight
342 KB
Volume
42
Category
Article
ISSN
0022-2135

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## Abstract The synthesis of a tosylate precursor for the radiosynthesis of a potential PET radiotracer, (S)‐N‐[(1‐ethyl‐2‐pyrrolidinyl)methyl]‐5‐(2‐[^18^F]fluoroethyl)‐2‐ methoxybenzamide is reported. Reaction of ^18^F‐fluoride with the tosylate provides the radiolabeled product in 10–25% yield. S