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Radiosynthesis of 3′-deoxy-3′-[18F]fluorothymidine: [18F]FLT for imaging of cellular proliferation in vivo

✍ Scribed by John R Grierson; Anthony F Shields

Book ID
117688465
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
698 KB
Volume
27
Category
Article
ISSN
0969-8051

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Preparation of 3′-deoxy-3′-[18F]fluoroth
Preparation of 3′-deoxy-3′-[18F]fluorothymidine ([18F]FLT) in ionic liquid, [bmim][OTf]
✍ Byung Seok Moon; Kyo Chul Lee; Gwang Il An; Dae Yoon Chi; Seung Dae Yang; Chang 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 128 KB

## Abstract Although 3′‐deoxy‐3′‐[^18^F]fluorothymidine ([^18^F]FLT) is a prospective radiopharmaceutical for the imaging of proliferating tumor cell, it is difficult to prepare large amount of [^18^F]FLT. We herein describe the preparation of [^18^F]FLT in an ionic liquid, [bmim][OTf] (1‐butyl‐3‐m