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Fast and efficient microscale radiosynthesis of 3′-deoxy-3′-[18F]fluorothymidine

✍ Scribed by Koag, Myong Chul; Kim, Hee-Kwon; Kim, Andrew Sungjoon

Book ID
127224869
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
337 KB
Volume
166
Category
Article
ISSN
0022-1139

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Preparation of 3′-deoxy-3′-[18F]fluoroth
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## Abstract Although 3′‐deoxy‐3′‐[^18^F]fluorothymidine ([^18^F]FLT) is a prospective radiopharmaceutical for the imaging of proliferating tumor cell, it is difficult to prepare large amount of [^18^F]FLT. We herein describe the preparation of [^18^F]FLT in an ionic liquid, [bmim][OTf] (1‐butyl‐3‐m