Radioimmunotherapy for Pancreatic Carcinoma Using131I-Labeled Monoclonal Antibody Nd2 in Xenografted Nude Mice
β Scribed by Inui, Akimasa ;Chung, Yong-Suk ;Sawada, Tetsuji ;Kondo, Yasuyuki ;Ho, Jenny J. L. ;Kim, Young-S. ;Sowa, Michio
- Book ID
- 108581268
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1996
- Tongue
- English
- Weight
- 568 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0910-5050
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Carbonic anhydrase IX (CA IX) is frequently expressed in human carcinomas and absent from the corresponding normal tissues. Strong induction by tumor hypoxia predisposes CA IX to serve as a target for cancer diagnostics and therapy. Here we evaluated targeting properties and pharmacokin
The monoclonal antibody (MAb) K1 is a murine IgG 1 that recognizes mesothelin, a differentiation antigen present on mesothelium which is highly expressed on cancers derived from mesothelium, including most ovarian cancers and epithelioid mesotheliomas. MAb K1 was conjugated to 2-(pisothiocyanatobenz