Radioimmunoassay for the quantitative determination of scopolamine
✍ Scribed by Elmar W. Weiler; Joachim Stöckigt; Meinhart H. Zenk
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 500 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0031-9422
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Atropine and scopolamine as free bases were simultaneously quantitated by GLC. Atropine and its sulfate salt produced peaks as apoatropine and atropine base. Scopolamine base produced peaks of scopolamine and a product of lower molecular weight. Linear standard curves were obtained between 0.5 and 2
A radioimmunoassay for a new anticancer drug, bruceantin, has been developed using [3H]acetylbruceantin and antibody induced by immunizing rabbits with succinylbruceantinbovine serum albumin conjugates. [3H]Acetylbruceantin was synthesized by reacting bruceantin with [3H]acetyl anhydride. The assay