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Radical releasing properties of nitric oxide donors GEA 3162, SIN-1 and S-nitroso-N-acetylpenicillamine

✍ Scribed by Päivi Holm; Hannu Kankaanranta; Timo Metsä-Ketelä; Eeva Moilanen


Book ID
119414593
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
116 KB
Volume
346
Category
Article
ISSN
0014-2999

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Cultured rat vascular smooth muscle cells (VSMCs) produce nitric oxide (NO) under stimulation by lipopolysaccharide (LPS) and interferon-y (IFN-y). NO synthase (NOS) and manganese superoxide dismutase (Mn-SOD) mRNA expressions are simultaneously induced by these stimulants in rat VSMCs. In VSMCs, S-