Radical prostatectomy for clinical T4 prostate cancer
β Scribed by Peter A. S. Johnstone; Kevin C. Ward; Michael Goodman; Vasily Assikis; John A. Petros
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 82 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
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The legitimate role of radical prostatectomy remains controversial. A prospective study was started at the Mayo Clinic in 1950 to evaluate therapeutic usefulness of the operation. Rigid criteria were established for selection of surgical candidates. From 1950 through 1972, 264 patients had radical p
## Abstract The results of this assessment of the literature indicated that neoadjuvant therapy followed by prostatectomy may improve longβterm outcomes for patients with highβrisk localized disease. In addition, this approach provides a paradigm for evaluating the activity and mechanism of action
W e commend Sonpavde et al 1 on their review of neoadjuvant therapy prior to prostatectomy, which focused on neoadjuvant drug trials. The bulk of preoperative intervention trials for prostate cancer utilize neoadjuvant chemotherapy, but we would like to comment on the use of preoperative radiotherap
## Abstract ## BACKGROUND Men with clinical stage T3a disease are at high risk and are often encouraged to undergo radiation therapy with concomitant hormonal therapy. The longβterm outcomes among men treated with radical prostatectomy for clinical stage T3a disease were examined. ## METHODS Amo