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Radical Cyclization in Heterocycle Synthesis. Part 10: A Concise Synthesis of (−)-Kainic Acid via Sulfanyl Radical Addition–Cyclization–Elimination Reaction

✍ Scribed by Okiko Miyata; Yoshiki Ozawa; Ichiya Ninomiya; Takeaki Naito


Book ID
108370916
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
173 KB
Volume
56
Category
Article
ISSN
0040-4020

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A Concise Synthesis of Rigidified β-Amino Acids via Sulfanyl Radical Addition-Cyclization of Oxime Ethers and Hydrazones. -Sulfanyl radical cyclization of alkenyl-tethered oxime ethers and hydrazones (I) provides cis/trans mixtures of the cyclized products (III) and (IV). The cyclopentylamines (III