Radical addition of protonated N-chloropiperidine to conjugated enynes
β Scribed by Poutsma, Marvin L.; Ibarbia, Pedro A.
- Book ID
- 125989883
- Publisher
- American Chemical Society
- Year
- 1971
- Tongue
- English
- Weight
- 441 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
Recently R.S.Neale' ha6 reported that the protonated I-ohloroemines add in good yield8 to oertain substituted olefine,partioularly vinyl chloroderivativee,whereas with unsubstituted olefina the reaotion oocur~ in low yields or doesn't at all.The reaeona adduced for thin
Palladium catalyzed addition of certain carbon pronucleophiles 2 to conjugated enynes l afforded the corresponding allenes 3 in good to excellent yields. The most reactive methynes such o.~ methylmalononitrile 2e enabled to undezgo double addition leading to alkenes 4. Catalyst optimization supporte
Palladium Catalyzed Addition of Carbon Pronucleophiles to Conjugated Enynes. -A new, catalytic route to the synthesis of differently substituted allenes is developed by addition of cyano-based carbon nucleophiles to conjugated enynes. Pd2(dba)3β’CHCl3/dppf is found to be the best catalytic system fo
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