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Radiation therapy-induced mucositis: Relationships between fractionated radiation, NF-κB, COX-1, and COX-2

✍ Scribed by Ann Yeoh; Rachel Gibson; Eric Yeoh; Joanne Bowen; Andrea Stringer; Kar Giam; Richard Logan; Dorothy Keefe

Book ID: 116395082
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 173 KB
Volume: 32
Category: Article
ISSN: 0305-7372
DOI: 10.1016/j.ctrv.2006.08.005

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## Abstract Enterovirus 71 (EV71) induces the expression of cyclooxgenase (COX)‐2 served as a major neurotoxic factor in CNS injury. However, the mechanisms underlying EV71‐initiated intracellular signaling pathways leading to COX‐2 expression remain unknown. Therefore, we investigated the mechanis