Enhanced radiation late effects and cell
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Susan Varghese; Rupert K. Schmidt-Ullrich; Anatoly Dritschilo; Mira Jung
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Article
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1999
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John Wiley and Sons
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English
β 577 KB
We observed severe late effects in a patient treated with radiation therapy for breast cancer. Radiation survival studies of patient fibroblasts show an enhanced cellular radiation sensitivity (Do = 0.95 Gy). Genetic analysis reveals that the patient is heterozygous for a mutated ATM gene. Protein t