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Radiation sensitive breast cancer patients

✍ Scribed by Norman, A.; Iwamoto, K.S.; Kagan, A.R.; Wollin, M.


Book ID
122697352
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
121 KB
Volume
23
Category
Article
ISSN
0167-8140

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We observed severe late effects in a patient treated with radiation therapy for breast cancer. Radiation survival studies of patient fibroblasts show an enhanced cellular radiation sensitivity (Do = 0.95 Gy). Genetic analysis reveals that the patient is heterozygous for a mutated ATM gene. Protein t